Research Publications

 

Leuchter AF, Jacobson SA. Quantitative measurement of brain electrical activity in delirium. International psychogeriatrics / IPA 1991;3:231-47.

 

Fogelson D, Jacobson S, Sternbach H. A retrospective study of valproate in a private psychiatric practice. Annals of Clinical Psychiatry 1991;3:315-320.

 

Lock J, Kleis B, Strouse T, Jacobson S, Yager J, Servis M. The role and function of residents' organizations in psychiatry education. Academic Psychiatry 1993;17:26-31.

 

Jacobson SA, Leuchter AF, Walter DO. Conventional and quantitative EEG in the diagnosis of delirium among the elderly. Journal of neurology, neurosurgery, and psychiatry 1993;56:153-8.

 

Jacobson SA, Leuchter AF, Walter DO, et al. Serial quantitative EEG among elderly subjects with delirium. Biological psychiatry 1993;34:135-40.

 

Ross BD, Jacobson SA, Villamil F, Korula J, Kreis R, Ernst T, Shonk T, Moats RA.  Subclinical hepatic encephalopathy: proton MR spectroscopic abnormalities. Radiology 1994;193:457-463.

 

Holzer JC, Jacobson SA, Folstein MF. Treating compulsive self-mutilation in a mentally retarded patient. The American journal of psychiatry 1996;153:133.

 

Jacobson S, Schreibman B. Behavioral and pharmacologic treatment of delirium.  American Family Physician 1997;56:2005-2012.

 

Jacobson SA. Delirium in the elderly. The Psychiatric clinics of North America 1997;20:91-110.

 

Boutros NN, Jacobson SA, Campbell D. Role of the unquantified electroencephalography in psychiatric research. CNS spectrums 1999;4:60-3.

 

Jacobson S, Jerrier H. EEG in delirium. Seminars in Clinical Neuropsychiatry 2000;5:86-92.

 

Jacobson S. Psychopharmacology in hepatic and renal failure (a CME article).  Psychiatric Times 2002 Nov XIX:65-69.

 

Jacobson SA, Folstein MF. Psychiatric perspectives on headache and facial pain. Otolaryngologic clinics of North America 2003;36:1187-200.

 

Jacobson SA, Dwyer PC, Machan JT, Carskadon MA. Quantitative analysis of rest-activity patterns in elderly postoperative patients with delirium: support for a theory of pathologic wakefulness. Journal of Clinical Sleep Medicine 2008;4:137-42.

 

Jacobson SA, Sabbagh MN. Donepezil: potential neuroprotective and disease-modifying effects. Expert Opinion on Drug Metabolism & Toxicology 2008;4:1363-9.

 

Ignatov I, Belden C, Jacobson S, et al. Possible Alzheimer's disease in an apolipoprotein E2 homozygote. Journal of Alzheimer's disease 2009;16:35-8.

 

Lue LF, Walker DG, Jacobson S, Sabbagh M. Receptor for advanced glycation end products: its role in Alzheimer’s disease and other neurological diseases. Future Neurology 2009; 4:167-177.

 

Cole L, Belden C, Jacobson S, Liebsack C, Myers K, Reninger C, Berk C, Sabbagh MN. Probable early-onset Alzheimer's disease in an apolipoprotein E2 homozygote. Dement Geriatr Cogn Disord 2010; 30:387-391.

 

Sabbagh MN, Malek-Ahmadi M, Kataria R, Belden CM, Connor DJ, Pearson C, Jacobson S, Yaari R, Singh U. The Alzheimer's questionnaire: a proof of concept study for a new informant-based dementia assessment. J Alzheimers Dis 2010; 22:1015-1021.

 

Adler CH, Hentz JG, Shill HA, Sabbagh MN, Driver-Dunckley E, Evidente VG, Jacobson SA, Beach TG, Boeve B, Caviness JN. Probable RBD is increased in Parkinson's disease but not in essential tremor or restless legs syndrome. Parkinsonism & Related Disorders 2011;17:456-8.

 

Damian AM, Jacobson SA, Hentz JG, et al. The Montreal Cognitive Assessment and the Mini-mental State Examination as screening instruments for cognitive impairment: item analyses and threshold scores. Dementia and Geriatric Cognitive Disorders 2011;31:126-31.

 

Jacobson SA, Sabbagh MN. Investigational drugs for the treatment of AD: what can we learn from negative trials? Alzheimer's Research & Therapy 2011;3:14.

 

Sabbagh MN, Fleisher A, Chen K, Rogers J, Berk C, Reiman E, Pontecorvo M, Mintun M, Skovronsky D, Jacobson SA, Sue LI, Liebsack C, Charney AS, Cole L, Belden C, Beach TG. Positron emission tomography and neuropathologic estimates of fibrillar amyloid-beta in a patient with Down syndrome and Alzheimer disease. Archives of Neurology 2011;68:1461-6.

 

Cabral D, Beach TG, Vedders L, Sue LI, Jacobson S, Myers K, Sabbagh MN. Frequency of Alzheimer's disease pathology at autopsy in patients with clinical normal pressure hydrocephalus. Alzheimer's & Dementia 2011;7:509-13.

 

Malek-Ahmadi M, Davis K, Belden C, Laizure B, Jacobson S, Yaari R, Singh U, Sabbagh MN. Validation and diagnostic accuracy of the Alzheimer's questionnaire. Age Ageing 2012;41:396-9.

 

Malek-Ahmadi M, Davis K, Belden CM, Jacobson S, Sabbagh MN. Informant-reported cognitive symptoms that predict amnestic mild cognitive impairment. BMC Geriatrics 2012;12:3.

 

Decourt B, Walker A, Gonzales A, Malek-Ahmadi M, Liebsack C, Davis KJ, Belden CM, Jacobson SA, Sabbagh MN. Can platelet BACE1 levels be used as a biomarker for Alzheimer's disease? Proof-of-concept study. Platelets 2013;24:235-8.

 

Boeve BF, Silber MH, Ferman TJ, Lin SC, Benarroch EE, Schmeichel AM, Ahlskog JE, Caselli RJ, Jacobson S, Sabbagh M, Adler C, Woodruff B, Beach TG, Iranzo A, Gelpi E, Santamaria J, Tolosa E, Singer C, Mash DC, Luca C, Arnulf I, Duyckaerts C, Schenck CH, Mahowald MW, Dauvilliers Y, Graff-Radford NR, Wszolek ZK, Parisi JE, Dugger B, Murray ME, Dickson DW. Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder. Sleep Med 2013;14:754-62.

 

Maarouf CL, Beach TG, Adler CH, Malek-Ahmadi M, Kokjohn TA, Dugger BN, Walker DG, Shill HA, Jacobson SA, Sabbagh MN, Roher AE; Arizona Parkinson’s Disease Consortium. Quantitative appraisal of ventricular cerebrospinal fluid biomarkers in neuropathologically diagnosed Parkinson's disease cases lacking Alzheimer's disease pathology. Biomarker Insights 2013;8:19-28.

 

Jacobson S. Laboratory testing in the diagnosis of Alzheimer’s disease: an update. Psychiatric News Update 2013:2(40):1-3.

 

Jacobson S. Effects of pharmacokinetic and pharmacodynamic changes in the elderly (a CME article). Psychiatric Times 2013 Jan:26-29.

 

Sabbagh MN, Malek-Ahmadi M, Dugger BN, Lee K, Sue LI, Serrano G, Walker DG, Davis K, Jacobson SA, Beach TG. The influence of Apolipoprotein E genotype on regional pathology in Alzheimer’s disease. BMC Neurology 2013;13:44.

 

Kokjohn TA, Maarouf CL, Daugs ID, Hunter JM, Whiteside CM, Malek-Ahmadi M, Rodriguez E, Kalback W, Jacobson SA, Sabbagh MN, Beach TG, Roher AE. Neurochemical profile of dementia pugilistica. Journal of Neurotrauma 2013;30:981-97.

 

Malek-Ahmadi M, Kahlon V, Adler CA, Obradov A, Thind K, Shill HA, Sue LI, Caviness JN, Jacobson S, Sabbagh MN. Prevalence of hippocampal sclerosis in a clinicopathologically characterized cohort. Clin Exp Med Sci 2013;1:317-27.

 

Henderson-Smith A, Chow D, Meechoovet B, Aziz M, Jacobson SA, Shill HA, Sabbagh MN, Caviness JN, Adler CH, Driver-Dunckley ED, Beach TG, Yin H, Dunckley T. SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening. PLoS One. 2013 Oct 30;8(10):e77711.

 

Roher AE, Maarouf CL, Malek-Ahmadi M, Wilson J, Kokjohn TA, Daugs ID, Whiteside CM, Kalback WM, Macias MP, Jacobson SA, Sabbagh MN, Ghetti B, Beach TG. Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations. Am J Neurodegener Dis. 2013;2:187-207.

 

Dugger BN, Adler CH, Shill HA, Caviness J, Jacobson S, Driver-Dunckley E, Beach TG; Arizona Parkinson's Disease Consortium. Concomitant pathologies among a spectrum of parkinsonian disorders. Parkinsonism & Related Disorders 2014;20:525-9.

 

Shill HA, Hentz JG, Jacobson SA, Belden C, Sabbagh MN, Beach TG, Driver-Dunckley E, Adler CH. Essential Tremor in the Elderly and Risk for Dementia. J Neurodegener Dis. 2014 328765.

 

Symanski C, Shill HA, Dugger B, Hentz JG, Adler CH, Jacobson SA, Driver-Dunckley E, Beach TG. Essential tremor is not associated with cerebellar Purkinje cell loss. Mov Disord. 2014;29:496-500.

 

Dugger BN, Hentz JG, Adler CH, Sabbagh MN, Shill HA, Jacobson S, Caviness JN, Belden C, Driver-Dunckley E, Davis KJ, Sue LI, Beach TG. Clinicopathological outcomes of prospectively followed normal elderly brain bank volunteers. J Neuropathol Exp Neurol. 2014;73:244-52.

 

Jacobson SA. Food interactions seen with many psychotropics. Psychiatric News. 2014; Vol 49 No. 13.

 

Adler CH, Beach TG, Hentz JG, Shill HA, Caviness JN, Driver-Dunckley E, Sabbagh MN, Sue LI, Jacobson SA, Belden CM, Dugger BN. Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic study. Neurology. 2014 Jul 29;83(5):406-12.

 

Maarouf CL, Kokjohn TA, Walker DG, Whiteside CM, Kalback WM, Whetzel A, Sue LI, Serrano G, Jacobson SA, Sabbagh MN, Reiman EM, Beach TG, Roher AE. Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease. PLoS One. 2014 Aug 28;9(8):e105784.

 

Jacobson SA, Simpson RG, Lubahn C, Hu C, Belden CM, Davis KJ, Nicholson LR, Long KE, Osredkar T, Lorton D. Characterization of fibromyalgia symptoms in patients 55-95 years old: a longitudinal study showing symptom persistence with suboptimal treatment. Aging Clin Exp Res 2015 Feb;27(1):75-82.

 

Jacobson SA, Morshed T, Dugger BN, Beach TG, Hentz JG, Adler CH, Shill HA, Sabbagh MN, Belden CM, Sue LI, Caviness JM, Hu C, and the Arizona Parkinson’s Disease Consortium. Plaques and tangles as well as Lewy-type alpha synucleinopathy are associated with formed visual hallucinations. Parkinsonism & Related Disorders 2014 Sep;20(9):1009-14.

 

Malek-Ahmadi M, Chen K, Davis K, Belden CM, Powell J, Jacobson, SA, Sabbagh MN. Sensitivity to change and prediction of global change for the Alzheimer's Questionnaire. Alzheimers Res Ther. 2015; Jan 8;7(1):1.

 

Dugger BN, Davis K, Malek-Ahmadi M, Hentz JG, Sandhu S, Beach TG, Adler CH, Caselli RJ, Johnson TA, Serrano GE, Shill HA, Belden C, Driver-Dunckley E, Caviness JN, Sue LI, Jacobson S, Powell J, Sabbagh MN. Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment. BMC Neurol. 2015 Aug 20;15:146.

 

Postuma RB, Adler CH, Dugger BN, Hentz JG, Shill HA, Driver-Dunckley E, Sabbagh MN, Jacobson SA, Belden CM, Sue LI, Serrano G, Beach TG. REM sleep behavior disorder and neuropathology in Parkinson's disease. Mov Disord. 2015 Sep;30(10):1413-7.

 

Sabbagh MN, Chen K, Rogers J, Fleisher AS, Liebsack C, Bandy D, Belden C, Protas H, Thiyyagura P, Liu X, Roontiva A, Luo J, Jacobson S, Malek-Ahmadi M, Powell J, Reiman EM. Florbetapir PET, FDG PET, and MRI in Down syndrome individuals with and without Alzheimer's dementia. Alzheimer’s Dement. 2015 Aug;11(8):994-1004.

 

Budolfson K, Malek-Ahmadi M, Belden CM, Powell J, Davis K, Jacobson S, Sabbagh MN. Neuropsychological Correlates of the Alzheimer's Questionnaire. J Alzheimer’s Dis. 2015;46(2):389-97.

 

Beach TG, Adler CH, Sue LI, Serrano G, Shill HA, Walker DG, Lue L, Roher AE, Dugger BN, Maarouf C, Birdsill AC,Intorcia A, Saxon-Labelle M, Pullen J, Scroggins A, Filon J, Scott S, Hoffman B, Garcia A, Caviness JN, Hentz JG, Driver-Dunckley E, Jacobson SA, Davis KJ, Belden CM, Long KE, Malek-Ahmadi M, Powell JJ, Gale LD, Nicholson LR, Caselli RJ, Woodruff BK, Rapscak, SZ, Ahern GL, Shi J, Burke AD, Reiman EM, Sabbagh MN. Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program. Neuropathology. 2015 Aug;35(4):354-89.

 

Filon JR, Intorcia AJ, Sue LI, Vazquez Arreola E, Wilson J, Davis KJ, Sabbagh MN, Belden CM, Caselli RJ, Adler CH, Woodruff BK, Rapscak SZ, Ahern GL, Burke AD, Jacobson S, Shill HA, Driver-Dunckley E, Chen K, Reiman EM, Beach TG, Serrano GE. Gender Differences in Alzheimer Disease: Brain Atrophy, Histopathology Burden, and Cognition. J Neuropathol Exp Neurol. 2016 Jun 12. pii: nlw047. [Epub ahead of print]

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Jacobson SA. Which metabolic panel for psychiatric practice: basic or comprehensive? Psychiatric News. April 7, 2017; Vol 52 No 7.​​